Name Name Polarity and Solubility Predictions Directions: Show your molecule below. Circle or highlight all polar portions of the molecule. Make a reasonable prediction about whether your molecule will be soluble in water or not and explain your reasoning. If your molecule seems to be borderline in polarity, making it difficult to predict solubility, explain your reasoning and the difficulty involved. Find a source (Merck Index, PDR, etc.) that discusses the water-solubility of your drug. Compare your predictions with the information you find on the water-solubility of your drug and comment on any discrepancies.. H # H CH H- H :0: 0: H