Problem 15.28 Both of the following syntheses will fail. Explain what is wrong with each one. (a) Step ( O O O O (1) HNO₁₂/H₂SO (2) CH₂COCI/AICI (3) Zn(Hg), HCI NO2 ) will fail because: rearrangements will occur during the Friedel-Crafts reaction. ortho-para substitution will occur. nitration can only proceed in the presence of strong base. a Friedel-Crafts reaction will not take place on a ring that bears any meta director.