20.7 In Alzheimer's disease, the number of neurons in the cortex de- creases as the disease progresses. The following data were taken to determine the number of neurotransmitter receptors left in a diseased brain. Free neurotransmitter ([F]) was incubated with tissue and the concentration that bound specifically to a receptor ([B]) was mea- sured. When binding is specific to a receptor, the concentration bound is related to the free concentration by the following relationship: [B] Bmax [F] K+ [F] Using the data below, determine the parameters that minimize the sum of the squares of the residuals. Also, computer². 10 20 [F], nM 0.1 0.5 1 5 50 [B], nM 10.57 36.61 52.93 82.65 89.46 94.35 101.00