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categoryالكيمياء schoolبكالوريوس event_available2026-07-15

السؤال

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1. The following transformation has been performed using a serine protease enzyme from the organism Streptomyces griseus. 30% S. griseus protease OEt Buffer pH 9.2 92% yield 85% e.e. OH (a) Illustrating your answer with equations and/or diagrams, explain and compare the terms Kinetic Resolution and Dynamic Kinetic Resolution with respect to the use of enzymes in organic synthesis. (b) Briefly illustrate the arrow-pushing mechanism by which the this hydrolysis reaction. (10 marks) enzyme achieves [4 marks) (c) Explain, with reasoning, how you might change the reaction conditions and/or reagents to achieve the synthesis of molecules A and B using the same enzyme (more than one reactions step may be needed). (6 marks) дов дави

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