تم الحل ✓
categoryهندسة كيميائية
schoolبكالوريوس
event_available2026-07-15
السؤال
Transcribed Image Text:
5. Cyclosporin A is produced by fermentation using either Cylindrocarpon lucidum Booth
or Tolypocladium inflatum Gams. The fermentation is carried out in batch reactors,
which are filled with a feed medium, inoculated with the fungi, and aerated for a period
of 13 days. The reactor product is milled and extracted with 90% methanol. The
methanol is evaporated off to give an aqueous solution that is then extracted with
ethylene chloride. The organic solution is evaporated to dryness and then the product is
purified by chromatography in methanol over aluminium oxide or silica gel. Sketch a
block flow diagram of the process.
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