cot- 5 in case ary nto EXERCISE 7-1 A donor sample from a 55-year-old white man demonstrated a positive antibody screen during routine processing testing. Results of testing with an antibody identification panel are shown. Refer to the panel to answer the following questions: ing Live ch- #88 Cell 1 R1R1 MNSS LISS P₁ Lewis Lutheran Kell Duffy Kidd DCECC MNSSP, Le Le Lu Lu Kk Fy Fy Jk Jk IS 37 IgG CC + on 2 R1R1 on 3 R2R2 + 4rr si- 5 Once 6 ள 7 RORO on ot 8 rr EE 6 Rh ++00+0++00++0+0+0+0+++000r 1+ 00++++0+0+0+0+0+0+0+002+ +00+++0+00000+0+++++0+000✓ 000+++0+0+++000+0+0+0+001+ 000++++++00+00+0++++0002+ 0 5- ly 10 R1R1 Patient cells ++00+0+0+0++ 11 1. At what phase are the reactions occurring? 2. What does the phase of the reaction suggest regarding the immunoglobulin class of antibody? 3. Is this an alloantibody or an autoantibody? 4. What is the most likely antibody specificity? 5. Are there antibodies that cannot be ruled out on this panel? 6. What additional testing should be performed to verify the specificity? What caused the production of this antibody in this donor? 8. Referring to the antigram, which cell or cells are homozygous for the S antigen? 9. Which cell is probably U-negative?